Under normal conditions when you setup replication between servers you want everything to flow: database a -> database b

In order for both databases to be in sync. all changes to database a must be replicated.

If you encounter a situation where you want to make a change, but do not want the commands to replicate you can disable bin logging:

set sql_log_bin = {0|1}

With the bin_log shut off, you can do any changes you need and they will not replicate.

The change applies to the current session only and will not impact your entire server.